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OxyContin side effects
If you experience the following allergic reaction to OxyContin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor immediately.

Like other narcotic medicines, oxycodone can slow your breathing. Death may occur if breathing becomes too weak. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Call your doctor at once if you have:

noisy breathing, sighing, shallow breathing;
a slow heart rate or weak pulse;
a light-headed feeling, like you might pass out;
confusion, unusual thoughts or behavior;
seizure (convulsions);
severe constipation; or
low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, confusion, fever, sweating, fast heart rate, chest pain, feeling short of breath, muscle stiffness, trouble walking, or feeling faint.

Serious side effects may be more likely in older adults and those who are malnourished or debilitated.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Common OxyContin side effects may include:

drowsiness, headache, dizziness, tired feeling; or
constipation, stomach pain, nausea, vomiting, loss of appetite.
dry mouth; or
mild itching.
OxyContin dosing information
Usual Adult Dose for Pain:

Initial:
Controlled Release (CR): 10 mg orally every 12 hours.

Maintenance:
CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximately 105 mg per day. Cancer patients with severe pain may require “as needed” rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form.

Usual Geriatric Dose for Pain:

Maintenance:
CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximately 105 mg per day. Cancer patients with severe pain may require “as needed” rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form.

Some drugs can raise or lower your blood levels of oxycodone, which may cause side effects or make oxycodone less effective. Tell your doctor if you also use certain antibiotics, antifungal medications, heart or blood pressure medications, or medicines to treat HIV or AIDS.

Narcotic (opioid) medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

other narcotic medications – opioid pain medicine or prescription cough medicine;
a sedative like Valium – diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others; or
drugs that make you sleepy or slow your breathing – a sleeping pill, muscle relaxer, tranquilizer, antidepressant, or antipsychotic medicine.
This list is not complete. Other drugs may interact with oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

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