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Name: zolpidem (zole PI dem)
Brand Names: Ambien, Ambien CR, Edluar, Intermezzo, Zolpimist

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Important Information about Ambien

Zolpidem, sold under the brand name Ambien, among others, is a medication primarily used for the short term treatment of sleeping problems. Guidelines recommend that it be used only after counseling and behavioral changes have been tried.

It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer.It is taken by mouth and is available in conventional tablets or sublingual tablets and oral spray.

Common side effects include daytime sleepiness, headache, nausea, and diarrhea. Other side effects include memory problems, hallucinations, and abuse. The recommended dose was decreased in 2013 due to next-morning impairment. Additionally driving the next morning is not recommended with either higher doses or the long acting formulation. While flumazenil can reverse zolpidem’s effects, usually supportive care is all that is recommended in overdose.

Zolpidem is a hypnotic and a nonbenzodiazepine of the imidazopyridine class.[3] Zolpidem is a type A GABA receptor agonist.[3] It works by increasing GABA effects in the central nervous system by binding to GABAA receptors at the same location as benzodiazepines.[3] It generally has a half-life of two to three hours.[3] This, however, is increased in those with liver problems.


Overdose can lead to coma or death.[4] When overdose occurs, there are often other drugs in the person’s system.[4][9] visit more

Zolpidem overdose can be treated with the benzodiazepine receptor antagonist flumazenil, which displaces zolpidem from its binding site on the benzodiazepine receptor to rapidly reverse the effects of the zolpidem. It is unknown if dialysis is helpful. read more


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